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Peptide guide

The top 50 research peptides, explained

What each peptide is, what people use it for, and how strong the evidence really is. Where vials have been lab tested, you can also see how every vendor's lab results compare.

For research use only. VendorVerify sells nothing and takes no money from vendors. No affiliate links, no coupon codes, no paid rankings. How scores work

What the evidence labels mean
Approved drug
Approved by the FDA for at least one use (the vials buyers test are research versions, not the approved product).
Approved outside the US
Approved as a medicine in other countries, not in the US.
Human trials
Tested in controlled human trials, whatever the result.
Early human data
Small, pilot or uncontrolled human studies only.
Animal/lab only
Evidence comes from animals or cells; effects in people are unproven.
Anecdotal
User reports only; no published studies.

Key facts

  • 10 of the 50 peptides on this list are approved by the FDA for at least one use.
  • 4 peptides are approved as a medicine outside the US but not in the US.
  • 11 peptides have been tested in controlled human trials without being approved.
  • 10 peptides have only small, pilot or uncontrolled human studies.
  • 13 peptides have evidence from animals or cells only.
  • 2 entries rest on user reports alone, with no published studies.
  • All 50 peptides on this list have a full VendorVerify guide.
  • 37 of the 50 peptides have independent lab results broken down by vendor.
  • The research vials buyers test are not the FDA-approved products, even for approved drugs.

Weight loss and metabolic

GLP-1 drugs, their newer relatives, and compounds sold for fat loss.

  • Tirzepatide

    Approved drug

    GIP and GLP-1 receptor agonist; approved as Mounjaro and Zepbound for type 2 diabetes and weight management.

  • Retatrutide

    Human trials

    Eli Lilly's investigational triple agonist (GIP, GLP-1 and glucagon receptors), several Phase 3 obesity and diabetes trials have reported, and it is not yet approved.

  • Semaglutide

    Approved drug

    GLP-1 receptor agonist; approved as Ozempic and Wegovy for type 2 diabetes and weight management.

  • Cagrilintide

    Human trials

    Long-acting amylin analogue from Novo Nordisk, studied alone and combined with semaglutide for weight loss.

  • Mazdutide

    Approved outside the US

    GLP-1 and glucagon receptor dual agonist from Eli Lilly, licensed to Innovent for China; approved there in 2025 for weight management and type 2 diabetes.

  • Survodutide

    Human trials

    Boehringer Ingelheim's GLP-1 and glucagon dual agonist; first Phase 3 obesity results published in 2026, liver-disease trials ongoing.

  • Liraglutide

    Approved drug

    Older, shorter-acting GLP-1 receptor agonist; approved as Victoza for diabetes and Saxenda for weight management.

  • Eloralintide

    Human trials

    Amylin receptor agonist from Eli Lilly; Phase 2 obesity results published in 2025 and Phase 3 trials under way.

  • AOD-9604

    Human trials

    Fragment of human growth hormone developed for fat loss; human trials did not show meaningful weight loss.

  • 5-Amino-1MQ

    Animal/lab only

    Not a peptide

    Small-molecule NNMT inhibitor sold alongside peptides; fat-loss data comes from mice.

  • MOTS-c

    Animal/lab only

    Mitochondria-derived peptide studied for insulin sensitivity and exercise capacity, mostly in animals.

Healing and recovery

Compounds buyers use for injuries, tendons, gut and skin repair.

  • BPC-157

    Animal/lab only

    Synthetic peptide based on a gastric protein sequence; studied for tendon, muscle and gut healing, almost entirely in animals.

  • TB-500

    Animal/lab only

    Synthetic peptide related to thymosin beta-4, sold for injury recovery; the research is on thymosin beta-4 and in animals.

  • KLOW / GLOW blends

    Anecdotal

    Vendor blend

    Vendor-made blends of BPC-157, TB-500 and GHK-Cu (KLOW adds KPV); the blends themselves have never been studied.

  • KPV

    Animal/lab only

    Tripeptide fragment of alpha-MSH studied for anti-inflammatory effects, including in gut inflammation models.

  • LL-37

    Early human data

    Human antimicrobial peptide (cathelicidin) studied as a topical gel for chronic leg ulcers; its infection claims come from lab studies.

  • ARA-290

    Early human data

    Peptide derived from erythropoietin (also called cibinetide), studied in small trials for nerve damage in sarcoidosis and type 2 diabetes.

  • Larazotide

    Human trials

    Gut tight-junction regulator studied for celiac disease; its Phase 3 trial was stopped in 2022.

  • PEG-MGF

    Animal/lab only

    Pegylated version of a peptide from an IGF-1 splice variant; the muscle-repair research used the plain peptide in cells and animals, and there are no human studies.

Growth hormone axis

Secretagogues and releasing-hormone analogues that raise GH or related hormones.

  • Tesamorelin

    Approved drug

    Growth hormone-releasing hormone analogue; approved as Egrifta to reduce abdominal fat in HIV-associated lipodystrophy.

  • Ipamorelin

    Human trials

    Selective growth hormone secretagogue (ghrelin receptor agonist), often paired with CJC-1295.

  • CJC-1295

    Early human data

    Long-acting growth hormone-releasing hormone analogue; the version without DAC is shorter-acting.

  • Sermorelin

    Approved drug

    US product discontinued

    Short GHRH analogue once FDA-approved for growth hormone deficiency in children.

  • Hexarelin

    Early human data

    Synthetic growth hormone secretagogue studied in small human studies.

  • GHRP-2

    Approved outside the US

    Growth hormone-releasing peptide (pralmorelin); approved in Japan only as a one-time diagnostic test for growth hormone deficiency, not as a treatment.

  • GHRP-6

    Early human data

    One of the first growth hormone-releasing peptides; acts on the ghrelin (hunger) receptor, and raises cortisol and prolactin as well as growth hormone.

  • IGF-1 LR3

    Animal/lab only

    Modified IGF-1 that escapes the body's IGF-binding proteins, made for cell-culture research; no human trials.

  • Gonadorelin

    Human trials

    US human products discontinued

    Synthetic gonadotropin-releasing hormone, once approved in the US for diagnostic testing and restoring ovulation; current listings are veterinary only.

  • HCG

    Approved drug

    Glycoprotein hormone

    Human chorionic gonadotropin; approved for fertility treatment and some forms of hypogonadism.

Skin, tanning and sexual health

Copper peptides, melanocortins and reproductive hormones.

  • GHK-Cu

    Early human data

    Copper-binding peptide found in human plasma; studied mainly in skincare, with little data on injection.

  • Melanotan II

    Early human data

    Synthetic melanocortin agonist that darkens skin and affects libido; unapproved, with safety concerns.

  • Melanotan I

    Approved drug

    Also called afamelanotide; approved only as the clinician-placed implant Scenesse for a rare light-sensitivity disorder (EPP), not for tanning.

  • PT-141

    Approved drug

    Bremelanotide; approved as Vyleesi for low sexual desire in premenopausal women.

  • Kisspeptin-10

    Human trials

    Fragment of kisspeptin, a hormone that switches on the reproductive axis; used in human research studies.

  • Oxytocin

    Approved drug

    Hormone approved to start or strengthen labor for medical reasons and control bleeding after birth; trials of its social and mood effects are mixed.

Longevity and mitochondria

Compounds studied for ageing, cellular energy and oxidative stress.

  • NAD+

    Early human data

    Coenzyme, not a peptide

    Coenzyme central to cellular energy; most human data is on its precursors (NR and NMN) rather than NAD+ itself.

  • SS-31

    Approved drug

    Elamipretide, a mitochondria-targeted peptide; granted FDA accelerated approval as Forzinity for Barth syndrome in 2025.

  • Epitalon

    Animal/lab only

    Synthetic tetrapeptide from pineal gland research, promoted for aging; evidence comes mostly from animals and one research group.

  • FOXO4-DRI

    Animal/lab only

    Peptide designed to clear senescent cells; studied in mice.

  • Humanin

    Animal/lab only

    Mitochondria-derived peptide studied for cell protection in animal and lab models.

  • Glutathione

    Human trials

    Tripeptide antioxidant made by the body; supplement trials show mixed results, and FDA has warned about endotoxin-contaminated compounded injectables.

  • Pinealon

    Animal/lab only

    Short synthetic peptide from the same research group as Epitalon, promoted for brain aging.

  • Thymulin

    Animal/lab only

    Zinc-dependent thymus hormone studied in animals for immune and inflammatory effects.

Cognition, mood and sleep

Nootropic and sleep peptides, several developed in Russia.

  • Semax

    Approved outside the US

    Synthetic ACTH fragment analogue approved in Russia, used there for stroke recovery and cognition.

  • Selank

    Early human data

    Russian-developed tuftsin analogue studied for anxiety; the clinical evidence is a few small Russian trials without a placebo group, plus a placebo-controlled brain-imaging study in healthy adults.

  • Adamax

    Anecdotal

    Sold as a Semax variant; we found no published study of any kind, not even one defining its structure.

  • DSIP

    Early human data

    Delta sleep-inducing peptide; small, mostly 1980s–90s sleep studies gave inconsistent results, and the positive ones came largely from one group.

  • Dihexa

    Animal/lab only

    Angiotensin IV analogue studied for memory in animals; the papers behind its proposed mechanism were retracted in 2025.

Immune

Thymic peptides and immune-signalling compounds.

  • Thymosin Alpha-1

    Approved outside the US

    Thymic peptide (thymalfasin) approved in a number of countries, not the US, mainly for hepatitis B; its largest sepsis trial was negative.

  • VIP

    Human trials

    Vasoactive intestinal peptide (aviptadil), studied in human trials for lung conditions; its largest COVID-19 trial was negative.